The Georgetown University Clinical Research Unit (GU-CRU), which is partially funded by a Clinical and Translational Sciences Award (CTSA) from the National Institutes of Health (NIH), offers the faculty of Georgetown University Medical Center and peer reviewed funded investigators from the partnering institutions of Georgetown-Howard Universities Center for Clinical and Translational Science (GHUCCTS) the optimal environment in which to conduct clinical research.

The Clinical Research Unit’s (CRU) mission is to sustain specialized institutional resources in which clinical investigators can observe and study human physiology as well as study and treat disease with innovative approaches. The objective of the GU-CRU program is to make available to medical scientists the resources that are necessary for the conduct of clinical research.

The GU-CRU does not fund specific research projects, but provides infrastructure and support in the form of inpatient beds, outpatient services, specialized research staff, and core equipment necessary to conduct studies. The unit supports hypothesis-based research regardless of funding source. These resources are available as a fee based service. Federally-funded studies may receive some 'no-cost' or reduced cost services based on scientific priority and the availability of resources. 

GU-CRU operates in collaboration with the clinical sites at other GHUCCTS institutions, including Howard University Clinical Research Unit, and investigators are encouraged to utilize resources from all sites.